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From70US$ /night
Check-in
11Mar2026Select date
Check-out
12Mar2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

4600 I-40 E, Amarillo, Texas, United States, 79103-6200
-
Near Splash Amarillo
Great
8.5
9.0
/10
4.2
/5

Accommodations

Best Western Santa Fe offers a variety of guest rooms including standard, accessible, and family rooms. Rooms include amenities such as microwaves, refrigerators, and satellite television to ensure a comfortable stay. The hotel provides non-smoking options for guests seeking a smoke-free environment.

Dining Options

The hotel features a complimentary hot breakfast, providing guests with a range of choices to start their day. A convenient on-site restaurant offers classic American cuisine for lunch and dinner. Nearby restaurants also present diverse dining options just a short walk away.

Location

Located off Interstate 40, Best Western Santa Fe is just minutes away from popular attractions such as the American Quarter Horse Hall of Fame and the Route 66 Historic District. The hotel's central positioning makes it easy to access the vibrant city of Amarillo. Nearby shopping and entertainment districts enhance the convenience of the location.

Business Amenities

The hotel provides a business center equipped with computers and printers for guest use. Meeting facilities are available, accommodating various sizes of groups and events. High-speed internet access in public areas enhances connectivity for business travelers.

Recreational Facilities

Best Western Santa Fe includes an indoor pool for relaxation and recreation. Guests can also unwind in the hot tub after a long day of travel. Fitness enthusiasts will appreciate the on-site fitness center with essential workout equipment.

Highlights

Accommodations: variety of guest rooms including family rooms

Dining: complimentary hot breakfast and on-site restaurant

Location: minutes from American Quarter Horse Hall of Fame

Business: business center and meeting facilities

Recreation: indoor pool and fitness center

“This is a solid choice, especially if you're traveling with pets; they're genuinely welcome here. I appreciate the Texas-sized waffles at the complimentary breakfast and the proximity to I-40 for quick trips, although you might need to keep an eye on traffic when pulling in. Clean rooms and an accommodating staff make for a reliable stay.”
Hotel logo
James DavidEditor-in-Chief at Cheaphotels
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Select your room type

The hotel provides a selection of rooms—doubles, family rooms, and suites—with perks like free cancellation, breakfast options, and great value deals
King Room Non-Smoking
2 persons
205 sq. feet 
1 King-size bed
Air conditioning
Queen Room Two Queen Beds
2 persons
205 sq. feet 
2 King Size Beds
Air conditioning
King Room Pet-Friendly or Non-Smoking
2 persons
205 sq. feet 
1 King-size bed
Air conditioning
Queen Room Two Queen Beds Pet-Friendly or Non-Smoking
2 persons
205 sq. feet 
2 King Size Beds
Air conditioning
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Amenities & services

Real traveler stories and honest reviews—no glossy ads, just authentic feedback to guide your booking
Facilities: Great
8.5/10Review score

General

  • No smoking on site
  • Internet access
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Vending machines
  • Smoke detectors
  • Fire extinguishers

Sports & Fitness

  • Golf course

Services

  • Housekeeping
  • Laundry

Business

  • Business centre
  • Fax/Photocopying

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Seasonal outdoor pool
  • Heated swimming pool
  • Beach umbrellas
  • Sun loungers

Room features

  • Air conditioning
  • Heating
  • Tea and coffee facilities
  • Ironing facilities

Media

  • AM/FM alarm clock
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Best Western Santa Fe Location

4600 I-40 E, Amarillo, Texas, United States, 79103-6200
Map view
4600 I-40 E, Amarillo, Texas, United States, 79103-6200
Nearby
1415 Sunrise Dr
Splash Amarillo
3400 ft
1415 Sunrise Dr
Starlight Ranch Event Center
3700 ft
Restaurants
El Charro Mexican Food
2000 ft
4207 I-40 East
Explore Amarillo
Local Highlights Near Best Western Santa Fe
Top Attractions
Activities
Dining
Entertainment
American Quarter Horse Museum
American Quarter Horse Museum
5-minute drive
A museum dedicated to the American Quarter Horse, featuring exhibits on history, breeding, and training.
Splash Amarillo
Splash Amarillo
17 minutes walking
A thrilling water park with slides and pools, ideal for family fun during warm weather.
Benton Park
13 minutes walking
A green oasis offering walking trails, playgrounds, and picnic areas, great for relaxation and outdoor activities.
Dick Bivins Stadium
5-minute drive
A sports venue known for its high school football games and community events, providing local excitement.
Mike's Amusement
15 minutes walking
An amusement center with arcade games and activities perfect for families and thrill-seekers.
Firewater Water Park
15 minutes walking
A local water park featuring pools and slides, ideal for relaxation and family outings during summer.
El Charro Mexican Food
El Charro Mexican Food
7 minutes walking
A casual spot offering authentic Mexican food with flavorful dishes; great for family meals.
Lucky's Amusement Ctr
20 minutes walking
A relaxed venue with a varied menu and games for all ages, perfect for family-friendly dining.
Tri-State Exposition
10-minute drive
A hub for fairs and events, hosting live music, food, and games for everyone to enjoy.
Amarillo Dillas Pro Baseball
20 minutes walking
A minor league baseball team offering thrilling games, a fun experience for family and sports fans.
Getting around town
City Centre
Amarillo9 min  ·  3.5 mi
Airports
Rick Husband Amarillo International Airport (AMA)15 min  ·  5.8 mi
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible at a location nearby for free.
Internet
High-speed internet access is available in public areas for free.
Breakfast
A american breakfast is served at affordable prices. 
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are allowed on request.
Number of rooms:
56

Reviews and Ratings

What past guests shared about their stay
Review score
Based on 260 verified reviews
8.8/10
Great
88%
Recommend
Breakfast
8.5/10
Cleanliness
9.0/10
Comfort
8.9/10
Facilities
8.5/10
Free Wi-Fi
9.1/10
Location
8.6/10
Paid Wi-Fi
8.0/10
Staff
9.3/10
Value for money
8.6/10
Pros
Clean room
Soft bed
Helpful staff
Good breakfast
Open windows
Cons
Warm water
Dark colors
Bathroom light
Guest reviews
based on 496 reviews
8.5/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
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FAQs
About Best Western Santa Fe
What are the check-in and check-out times at Best Western Santa Fe?
Check-in is from 15:00 and check-out is by 11:00.
What nearby attractions can guests visit when staying at Best Western Santa Fe?
Nearby attractions include American Quarter Horse Hall of Fame & Museum (5 km), Amarillo Botanical Gardens (8 km), and Big Texan Steak Ranch (3 km).
What amenities does Best Western Santa Fe provide for business travelers?
The hotel features a business center, express check-in/out, and complimentary wireless Internet access.
Is there a swimming pool at Best Western Santa Fe?
Guests can enjoy a seasonal outdoor pool at the hotel.
What room amenities are available at Best Western Santa Fe?
Rooms include air conditioning, a flat-screen TV, a fridge, a coffee machine, and free toiletries.
Does Best Western Santa Fe offer breakfast options?
A complimentary full breakfast is served daily, featuring Texas-shaped waffles, yogurt, and pastries.
How far is Best Western Santa Fe from Rick Husband Amarillo International Airport?
The hotel is located 5 km from Rick Husband Amarillo International Airport, approximately a 15-minute drive.
What leisure activities are available at Best Western Santa Fe?
Guests can enjoy access to a seasonal outdoor pool and a golf course for recreation.
Can guests access internet services at Best Western Santa Fe?
Free wireless Internet access is provided throughout the hotel.

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Check-in
11Mar2026Select date
Check-out
12Mar2026Select date
Rooms and Guests2 Guests, 1 Room